What are SARMs?

SARMS, or selective androgen receptor modulators, are a unique class of molecules that are being developed to treat diseases that are currently being treated with AAS (anabolic-androgenic steroids). Some SARMS have even gone to trial for TRT (testosterone replacement therapy).

When SARMS bind to the receptor they demonstrate anabolic and hypertrophic activity in both muscle and bone. This makes them ideal candidates for TRT, osteoporosis treatment and muscle wasting treatment.

For bodybuilders, SARMS provide the benefits of traditional AAS (anabolic-androgenic steroids) - more muscle, less fat, and better bone density - while producing significantly fewer unwanted side effects (estrogen related sides and water retention).

SARMS can have an anabolic to androgenic ratio as high as a 10:1. This is what allows them to build muscle with little to no side effects. They also typically display a high bioavailability, ensuring effective utilisation and absorption.

Popular Sarms on the market

MK-2866 (Ostarine) Powder
S4 (Andarine) powder
S-23 sarm powder
mk 677 (ibutamoren) powder
GW-501516 (Cardarine) powder
LGD-4033 (Anabolicum) powder
SR-9009 (Stenabolic) powder
RAD-140 (Testolone) powder

Benefits of SARMs over AAS

SARMS are nontoxic to the liver and have little effect on blood pressure. This eliminates the need for preloading and on-cycle support supplements. Subsequently, a SARM cycle will ultimately be less expensive than a traditional AAS/Ph (steroid/prohormone) cycle. The chances of estrogen-related sides and water retention are significantly lower, as well. 

SARMs, PPAR modulators & GH secretagogues

LGD 4033 powder for sale
LGD 4033 a SARM like Ostarine but 12 times as powerful at only 1/3 the dose! Consequently it is more suppressive to the HPTA (Hypothalamus-Pituitary-Testes-Axis – the system of the hypothalamus, pituitary gland and gonadal glands, which plays a vital role in the development and regulation of the reproductive and immune systems). So, a SERM (selective estrogen receptor modulator) post cycle therapy is recommended.

Where Ostarine is best used in a cutting cycle, LGD has proven itself as a good bulking agent. LGD has a half-life ranging between 24 and 36 hours so daily dosing is optimal.

In a study performed at Boston University, healthy men who were given 1mg of LGD daily gained about 3 pounds in 3 weeks on average. No clinically significant changes were noted in liver function tests, PSA (prostate issue/function tests), hematocrit (testing on the ratio of the volume of red blood cells to the total volume of blood) or ECG (electrocardiogram tests, used to check the heart's rhythm and electrical activity).

However, given the potential for high estrogen side effects while using LGD, it is recommended that you have an AI like Exemestane on hand.

LGD example cycle

Beginner
LGD 4/4/4/8/8/8
OL Eliminate 2/2/2/2/2/2
PCT:

OL SUP3R PCT as indicated on label
AI of choice on hand

Advanced
LGD 4/4/8/8/8/8/12/12
OL Eliminate 2/2/3/3/3/3/3/3
PCT:

OL SUP3R PCT as indicated on label
AI of choice on hand
*Ar1macare Pro can be substituted for Elim1nate during cycle for full protection


MK 677 (Ibutamoren) Powder cheap price UK
This is a non-peptidic, orally active and selective agonist of the growth hormone secretagogue (secretion-boosting) receptor. It mimics the action of ghrelin (the hormone that regulates appetite and the distribution and rate of use of energy) in the stomach, raising growth hormone and IGF-1 levels, but does not affect cortisol levels.

Human studies have shown it to increase both muscle mass and bone mineral density. Dosed at 25mg daily, Ibutamoren has been shown to increase IGF-1 levels by 60% in 6 weeks in humans. A 72% increase in IGF-1 levels was seen after 12 months.

MK 677 is non-hormonal and therefore requires no PCT after the cycle is over. It is best utilised in at least a 3 month cycle with dosage increasing each month. The optimal dosing time for MK 677 is at night directly before going to bed. You should start to notice a deeper sleep almost immediately. If you should wake up with numb or tingly hands, do not worry. This is a common side effect of the extra GH in the system.

MK 677 example cycle

Month 1 - 10mg once daily
Month 2 - 20mg once daily
Month 3 - 30mg once daily
 
GW 501516 cardarine powder
This is actually not a SARM. In fact it is a PPAR Delta Modulator – a selective agonist with a high affinity for the PPAR (peroxisome proliferator-activated receptors - a group of steroid- and thyroid-sensing proteins that control the expression of genes, thereby regulating cellular development and metabolism). This modulation allows the body to utilise more glucose and create more muscle tissue.

GW also regulates the various proteins that the body uses for energy. For the user, this means an increase in energy and endurance, and it may also mean an increase in muscle mass. It is also possible that GW might have a positive effect on blood pressure and lipid profile.

Dosing is in the 7mg to 21mg range, with 14mg being the "sweet spot". The average GW cycle is typically 4 to 12 weeks. GW is non-hormonal and therefore requires no PCT. However, it does stack well with SARMS to further increase fat loss and endurance.

GW 505516 example cycle

Beginner
GW 7/7/14/14/14/14

Intermediate
GW 7//14/14/14/14/21

Advanced
GW 14/14/14/14/21/21/21/21

 
RAD 140
RAD 140 is very new, so there isn't a lot of real world data on it yet. However, it does look very promising, with an impressive anabolic to androgenic ratio of 90:1! This means that users can experience a wealth of muscle building effects without all the associated androgenic side effects.

RAD is powerful enough to limit the effect of testosterone on the prostate and other unwanted areas. It has even been shown to be more anabolic than testosterone, as well. Dosing appears to be in the 4mg to 12mg range, with optimal cycle length being 4 to 6 weeks. Given its shorter half-life (16 hours), RAD needs to be dosed at least twice daily.

RAD 140 example cycle

RAD 140 4/4/8/8/12/12
PCT:
OL SUP3R PCT as indicated on label
*Also have AI of choice on hand
*Armicare Pro can be used during cycle for full protection

Ostarine mk2866
This is probably the most well-known SARM. It is best used to preserve muscle mass while in a caloric deficit. Ostarine can and will suppress your natural testosterone production in longer, higher dosed cycles, so a SERM PCT is needed. Ostarine can also cause gyno in some users, so it is recommended that you have an AI, like Exemestane, on hand.

The average cycle length is 6 to 10 weeks at a dosage range of 10mg to 25mg.

Ostarine example cycle

Beginner cut
Ostarine - 15/15/15/15/15/15
PCT:
OL SUP3R PCT as indicated on label
 
Advanced cut
Ostarine - 15/15/15/15/15/20/20/20/20/20
OL ELIM1NATE - 2/2/2/2/2/3/3/3/3/3
PCT:
OL SUP3R PCT as indicated on label
 
Recomp cycle
Ostarine - 20/20/20/20/25/25/25/25
PCT:
OL SUP3R PCT as indicated on label
 

SARM cycle stacks

Here are some SARM cycle stacks that I've come up with....
 
Cut to bulk
Ostarine -15/15/15/15/15/15/0/0/0/0
LGD - 0/0/0/0/4/4/8/8/12/12
PCT: 
OL SUP3R PCT as indicated on label
 
RAD/Osta recomp
RAD - 4/4/8/8/12/12/0/0
Ostarine - 20/20/20/20/25/25/25/25
PCT:
OL SUP3R PCT as indicated on label
 
RAD/LGD bulk
RAD - 4/4/8/8/12/12/0/0
LGD - 4/4/4/8/8/8/12/12
PCT:
OL SUP3R PCT as indicated on label
 
MK 677 and/or GW501516 would stack great with these cycles as well, and would also help with endurance, sleep and overall muscle gain. 

SARMs boast many of the benefits of traditional anabolic steroids minus the side effects
They can help build muscle, burn fat and improve bone density
They give rise to fewer estrogen-related sides and less water retention
They are nontoxic to the liver and have little effect on blood pressure
However, they must still be dosed and cycled correctly, as outlined above
They may be stacked to achieve the desired effects (recommendations above)